The Dynamic AVF: Fully implantable, magnetically actuated with 100% velocity reduction in the fistula

The innovative technology seamlessly connects the artery and vein only during dialysis, while keeping the AVF closed during the rest of the time and ensuring  normal blood circulation:

  • The DAVF is implanted using standard vascular surgical techniques, incorporating a short (<1 cm) graft segment between the vessels
  • The DAVF is controlled entirely  through a non-invasively patented magnetic activator
  • The actuator opens the arteriovenous fistula , enabling the high blood flow necessary for dialysis
  • Following dialysis, the graft fully closes, stopping blood flow through the fistula (0 ml/min) and restoring the normal blood circulation
  • Patented technology is included that eliminates voids in the graft when in closed position, effectively preventing thrombosis

With the DAVF the blood flow can be controlled to an optimal value of 600 ml/min for hemodialysis or restore to normal during daily life. A 90% reduction in time that the high blood flow is present will minimize complications for the patient and help to improve their overall quality of life

    • Restore normal blood circulation and remove turbulent flow, which in turn reduces stenosis formation and maintain access patency
    • Restore systemic vascular resistance, which decreases cardiac output and reduces heart failure
    • Decrease blood flow after dialysis session, which reduces compression time and risk of bleeding
    • Restore normal blood circulation, which reduces risk on steal syndrome
    • Decrease continuous presence of high flow, which reduces aneurysm

The Dynamic AVF is a very promising new type of vascular access that could result in a strong reduction of vascular access-related complications such as poor access patency, cardiac stress and steal syndrome.

Dirk Hentschel

Director of Interventional Nephrology at Brigham and Women’s Hospital in Boston and Key Opinion Leader on vascular access for hemodialysis